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A producer cell with a diameter of 1 µm was placed in the middle of a very thin rectangular block (1.1 µm thickness) to represent a quasi-two-dimensional system. For the three-dimensional system it was placed in the middle of a cube. For the cube, concentrations at the cube boundaries were set to zero. For the thin plate the concentrations at the four lateral faces were set to zero, and the top and bottom boundaries were insulated (no-flux boundary condition). The total volume of both systems was 1 nL (1·10 6 cells/mL). A time dependent study in COMSOL <t>Multiphysics</t> yielded concentration gradients at several moments. The figure shows the concentrations along the diagonal after 5 hours.
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A producer cell with a diameter of 1 µm was placed in the middle of a very thin rectangular block (1.1 µm thickness) to represent a quasi-two-dimensional system. For the three-dimensional system it was placed in the middle of a cube. For the cube, concentrations at the cube boundaries were set to zero. For the thin plate the concentrations at the four lateral faces were set to zero, and the top and bottom boundaries were insulated (no-flux boundary condition). The total volume of both systems was 1 nL (1·10 6 cells/mL). A time dependent study in COMSOL Multiphysics yielded concentration gradients at several moments. The figure shows the concentrations along the diagonal after 5 hours.

Journal: bioRxiv

Article Title: Microbial competition reduces interaction distances to the low µm-range

doi: 10.1101/2020.01.22.915835

Figure Lengend Snippet: A producer cell with a diameter of 1 µm was placed in the middle of a very thin rectangular block (1.1 µm thickness) to represent a quasi-two-dimensional system. For the three-dimensional system it was placed in the middle of a cube. For the cube, concentrations at the cube boundaries were set to zero. For the thin plate the concentrations at the four lateral faces were set to zero, and the top and bottom boundaries were insulated (no-flux boundary condition). The total volume of both systems was 1 nL (1·10 6 cells/mL). A time dependent study in COMSOL Multiphysics yielded concentration gradients at several moments. The figure shows the concentrations along the diagonal after 5 hours.

Article Snippet: To compare concentration gradients in two- and three-dimensional systems we made reaction-diffusion models in COMSOL Multiphysics (supplementary information, ).

Techniques: Blocking Assay, Concentration Assay

Journal: bioRxiv

Article Title: Microbial competition reduces interaction distances to the low µm-range

doi: 10.1101/2020.01.22.915835

Figure Lengend Snippet:

Article Snippet: To compare concentration gradients in two- and three-dimensional systems we made reaction-diffusion models in COMSOL Multiphysics (supplementary information, ).

Techniques: